目的：探究 3D 单孔胸腔镜在非小细胞肺癌（NSCLC）手术中的应用效果及对患者术后恢复的影响。方法：选取 2022 年 8 月—2024 年 8 月南通市肿瘤医院行 NSCLC 手术的 150 例患者，依据手术方式分为研究组（n=78）和对照组（n=72）。对 照组采用 2D 单孔胸腔镜手术治疗，研究组采用 3D 单孔胸腔镜手术治疗，比较两组患者手术相关指标、血清指标、免疫指标、 术后并发症发生情况。结果：两组在术中出血量、淋巴结清扫数目、术后留管时间、术后 72 h VAS 评分方面的差异无统计 学意义（P>0.05），但研究组手术时间长于对照组，住院时间、术后引流量、术后 24 h VAS 评分均低于对照组（P<0.05）。 相较于术前，两组术后1 d Cor、去甲肾上腺素（NE）、丙二醛（MDA）水平均升高，超氧化物歧化酶（SOD）水平均降低（P<0.05）， 且研究组术后 1 d Cor、NE、MDA、SOD 水平均优于对照组（P<0.05）。研究组术后 7 d IgA、IgM、IgG 均高于对照组（P<0.05）， 且并发症总发生率较低（P<0.05）。结论：3D 单孔胸腔镜在 NSCLC 手术中的应用效果良好，可有效缓解患者术后疼痛，改 善免疫功能，减少应激反应和术后并发症发生率，促进术后恢复。

Objective: To investigate the efficacy of 3D single-port thoracoscopic surgery in the treatment of non-small cell lung cancer (NSCLC) and its impact on patients’ postoperative recovery. Methods: 150 NSCLC patients who underwent surgery at Nantong Tumor Hospital from August 2022 to August 2024 were enrolled. They were divided into the study group (n=78) and the control group (n=72) according to different surgical approaches. The control group received 2D single-port thoracoscopic surgery, while the study group underwent 3D single-port thoracoscopic surgery. Surgical indicators, serum markers, immune markers, and postoperative complications were compared between the two groups. Results: No statistically significant differences were observed between the two groups in intraoperative blood loss, number of lymph nodes dissected, drainage tube retention time, or VAS scores at 72 h after surgery(P>0.05). However, longer operative time, shorter length of hospital stay, reduced postoperative drainage volume, and lower VAS scores at 24 h after surgery were observed in the study group compared to the control group (P<0.05). Increased levels of cortisol (Cor), norepinephrine (NE), malondialdehyde (MDA), and decreased superoxide dismutase (SOD) levels were observed in both groups 1 day after surgery(P<0.05), and they were better in the study group than the control group (P<0.05). At postoperative day 7, higher IgA, IgM and IgG levels were observed in the study group (P<0.05), and the total complication rate was significantly lower (P<0.05). Conclusion: The application of 3D singleport thoracoscopic surgery in the treatment of NSCLC can achieve favorable outcomes, effectively alleviate postoperative pain, improve immune function, reduce stress responses and complication rates, and promote postoperative recovery.

基金项目：南通市卫生健康委员会科研项目（ms2022047） 

Foundation Item: Scientific Research Project of Nantong Municipal Health Commission (ms2022047) 

引用格式：吴红霞，陆玉珠，陆敏敏 .3D 单孔胸腔镜在非小细胞肺癌手术中的应用及对患者术后恢复的影响 [J]. 机器人外科学杂志（中英文）， 2025，6（5）：819-823. 

Citation: WU H X, LU Y Z, LU M M. Application of 3D single-port thoracoscopic surgery in the treatment of non-small cell lung cancer and  its impact on patients’ postoperative recovery[J]. Chinese Journal of Robotic Surgery, 2025, 6(5): 819-823. 

通讯作者（Corresponding Author）：陆敏敏（LU Minmin），Email：minmin_66@163.com

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